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doi: 10.1016/j.jphotochem.2022.114340 27 BajwaU.SandhuK

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Stimulation with 6-hydroxydopamine (6-OHDA) markedly downregulates nuclear factor erythroid 2related factor 2 (NRF2) expression in PC-12 cells, elevates Fe 2+ and reactive oxygen species (ROS) levels, suppresses glutathione peroxidase 4 (GPX4), promotes both ferroptosis and apoptosis, inhibits cell proliferation, and causes neuronal damage

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However, its important to consult a healthcare expert before starting any glutathione supplements to ensure the right dosage and prevent potential interactions with other medications